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Using two separate drugs to lose weight naturally can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err to the side of caution and allow the FDA do its job and demand some research be done so your public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to make money and that they would say almost anything to keep people on their medications. Researchers found out that participants taking this drug to get a year, lost excess weight within 4 weeks and have kept the weight off during the entire 56 weeks in the study. Contrave can be a combination of the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs that are made up of multiple active ingredient, which might make them more potent and safer. Combo-pilling will be the newest fad or better yet the newest into the future under scrutiny and so it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug can also raise blood pressure level and pulse rate, and really should not be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure levels, in addition to by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. 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