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Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you ought to err assisting caution and permit the FDA do its job and demand some research be done so that the public recognizes the side effects and dangers of the medications before we take them. Keep in mind that drug companies are in business to make money and that they would say everything to keep people on their medications. Researchers discovered that participants investing in this drug for a year, lost excess weight within one month and have kept the body weight off through the 56 weeks in the study. Contrave is a combination of the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which are made up of multiple active ingredient, that might make them more efficient and safer. Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular could be the fact that since right now there aren't any long term prescription weight loss supplements that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug could also raise hypertension and heart rate, and really should not be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not be used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients on the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation. 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